Professor Marcelle Machluf, Ph.D
Prof. Marcelle Machluf received her Ph.D. in Biotechnology Engineering from the Ben-Gurion University (Israel). Marcelle went on to complete a 5-year post-doctoral fellowship at the Harvard Medical School under the supervision of Prof. Anthony Atalla. Marcelle joined the Technion in 2001, and received tenure in 2007; in 2014, she was promoted to full professor. Prof. Machluf has authored 40 peer-reviewed journal papers, co-authored 15 papers, and published over 100 conference papers. Her papers have appeared in leading generalized and specialized journals including Nature Biotechnology, Nano Letters, and Blood, and have been cited over 2,500 times, awarding her an h-index of 26 (Google Scholar). Prof. Machluf has supervised more than 40 graduate and post-doctoral students, from around the world, and is teaching four undergraduate and graduate courses in nano-encapsulation, tissue engineering, mammalian cell technologies, and bioprocessing. Prof. Machluf is a member of the TargetCaRe consortium, under Horizon 2020 Training Networks (H2020-MSCA-ITN-2014). Prof. Machluf is the head of a six-year collaboration between six groups from the Technion and two of Singapore’s leading universities (NTU and NUS) funded by the National Research Foundation of Singapore. Prof. Machluf is a member of the Minerva Programme Committee, under the Max-Planck Institute (Germany) and a member of the Tissue Engineering Journal editorial board. Prof. Machluf is the Head of the Technion’s Graduate Interdisciplinary Program in Biotechnology and was recently appointed as the Deputy Executive Vice President for Research For the Pre-clinical Research Authority of the Technion.
Dr. Limor Baruch, Ph.D.
Dr. Limor Baruch, Senior research fellow, co-lab manager, and Tissue Engineering and cell-based therapy group leader. Limor received her Ph.D. in Biotechnology Engineering from the Technion, under the supervision of Prof. Machluf. Limor’s dissertation presented the development of two cell- microencapsulation platforms and their application for cancer treatment. In 2008, Dr. Baruch established the laboratory for crop quality at Kaiima Bio-Agritech Ltd. and managed it for six years. Dr. Baruch’s expertise includes the setup of laboratories and research fields, diverse analytical methodologies and scientific consultancy in addition to cell-based therapy, drug delivery systems and regenerative medicine.
Ms. Inna Kovrigina, M.Sc, Lab technician. E-mail: email@example.com (profile under construction)
Post & Graduate Students
Dr. Anton Zernov, Ph.D., postdoc
Anton completed his M.Sc and Ph.D. in bioengineering and biotechnology in the Faculty of Biology, M.V.Lomonosov Moscow State University, and Federal Research Centre “Fundamentals of Biotechnology”, Russian Academy of Science. Now he is currently a postdoc. His research focuses on the development and investigation of mesenchymal stem cells membrane-derived nanoghosts with encapsulated gold nanoparticles for diagnostics and photodynamic therapy of cancer. Also, his interests include the development and investigation of clean meat.
Tzila Davidov, M.Sc, Ph.D. student
Tzila completed her B.Sc in the Faculty of Biotechnology and Food Engineering at the Technion and is currently a Ph.D. student. Her research focuses on the effect of the ECM origin in structuring 3D models, and its influence on the function and the differentiation of cells, such as induced pluripotent stem cells (hiPSCs) into the desired cell and tissue type. Tzila has received the Yitzhak Navon Ph.D. Fellowship from the Israel Ministry of Science, given to women living on the socioeconomic periphery for academic excellence.
Avraham Fridman, M.Sc, Ph.D. student
Avraham completed his B.Sc. in Pharmaceutical Engineering at the Azrieli College of Engineering Jerusalem, completed his M.Sc. in Pharmaceutical Sciences at the Hebrew University of Jerusalem, and is currently a Ph.D. student. His research focuses on the applications of Nano-Ghosts from mesenchymal stem cells for inflammation therapy and as a drug delivery system with the capacity to pass across the blood-brain-barrier (BBB) targeting brain inflammation.
Avraham has received the PBC Scholarship for Outstanding Graduate Students.
Rotem Hayam, M.Sc, Ph.D. student
Rotem completed her B.Sc in the Faculty of Chemistry Engineering at the Technion and is currently a Ph.D. student. Her research focuses on the development of advanced Extracellular Matrix processing technologies for Tissue Engineering.
Michal Skitel, M.Sc, Ph.D. student
Michal completed her B.Sc in Biotechnology at the Hadassah Academic College and is currently a Ph.D. Student. Her research focuses on Extracellular Matrix (ECM) based therapy for diabetes. In this research, the ECM is engineered as microcapsules to support islets viability. Michal has received the Ariane de Rothschild scholarship, given to female Ph.D. students for academic excellence.
Shani Hamias, M.Sc, Ph.D. student
Shani completed her B.Sc in the Faculty of Chemistry Engineering at the Technion and is currently a Ph.D. student. Her research focuses on a novel drug delivery system aimed to selectively target brain cancer across the Blood-Brain Barrier (BBB) using MSCs derived vesicles (nano-ghosts).
Maksim Kazarnovskiy, M.Sc, Ph.D. student
Maksim graduated from Moscow State University, where he got a Pharmacy degree. His research is focused on immune-oncology and anti-cancer medication development using MSC-derived vesicles (nano-ghost) as carriers for the drug.
Anastasia Brandis, M.Sc, Ph.D. student
Anastasia completed her B.Sc. in the Faculty of Biology at the Herzen University, completed her M.Sc. in biotechnology at the ITMO University in Saint-Petersburg and is currently a Ph.D. student. Her research is focused on an inflamed cardiac tissue treatment using MSCs derived vesicles (Nano-ghost) as a drug delivery system.
Shira Levi, M.Sc student
Shira completed her B.Sc in the Faculty of Biotechnology and Food Engineering at the Technion and is currently an MSc student. Her research focuses on the development of scaffolds for cultured meat.
Frank (Feng-Chun) Yen, M.Sc student
Frank (Feng-Chun) Yen completed his B.Sc in the Department of Biological Science and Technology at National Chiao Tung University in Taiwan and is currently an MSc student. His research focuses on developing cultured meat platforms based on scalable cellular building blocks. Frank is also establishing efficient and scalable culturing methodologies using bioreactor.
Shay Bamany, M.Sc student
Shay completed his B.Sc in the Faculty of Biotechnology and Food Engineering at the Technion and is currently an MSc student. His research focuses on creating a safe and potent immunization platform against SARS-CoV-2 using mesenchymal stem nano-vesicles (Nano-Ghosts).
Amir Betker, M.Sc student
Amir completed his B.Sc in the Faculty of Biotechnology and Food Engineering at the Technion and is currently an M.Sc student. His research focuses on creating an immunotherapeutic system using mesenchymal stem nano-vesicles (Nano-Ghosts).