The TargetCaRe consortium aims to develop treatments for joint and intervertebral disc diseases by combining advanced drug delivery carriers with dedicated targeting tools, state of the art imaging techniques and expertise in biology of stem cells and joints. The consortium consists of world-leading scientists from 14 institutions in 5 countries. All scientists are renown experts in their field of research, such as stem cell biology, biomaterial technology, in vivo imaging, nanomedicine and mass spectrometry imaging.
Funded by The European Commission under Horizon 2020 (H2020-MSCA-ITN-2014).
START is located in the CREATE Research Wing, funded by National Research Foundation, Singapore. The universities involved in this center are the Technion-Israel Institute of Technology (Technion), Nanyang Technological University (NTU), National University of Singapore (NUS) and National University Health System (NUHS). This research program focuses on Regenerative Medicine in Cardiac Restoration Therapy through tissue engineering, cell-therapy, and acellular device-based approaches. Cardiac regenerative medicine is a treatment strategy that aims to improve the function of damaged myocardium by promoting the formation of new contractile cardiac tissue. It applies a systematic and practical approach to overcome the clinical, scientific, and technological hurdles that impede cardiac restoration.
To date, we have successfully refined out porcine cardiac extracellular matrix (pcECM) technology to produce thick acellular scaffolds with inherent vasculature that resemble the native tissue, and can support the long term survival of several progenitor cardiac cells. We are implementing our scaffold technology with or without cardio-myogenic progenitor cells in vivo; showing biocompatibility and efficacy in myocardial infarction.
Video: Forever Young – Short Documentary (Regenerative Medicine/Life Extension)
Funded by The National Research Foundation (NRF) of Singapore under the C.R.E.A.T.E center.
Technion-NYU collaborative grant initiative
Prof. Marcelle Machluf (Technion) and Prof. Eva Hernando (NYU) – Novel nanotechnology approach against melanoma brain metastasis.
Supported by a generous gift from Ike and Laurie Perlmutter.
Tissue Engineered Heart Construct: Bridging the Gap between Ex- and In Vivo Mechanical Effects Towards Clinical Achievements
Prof. Marcelle Machluf (Technion) and Prof. Brigadier General (Ret.) Jacob Bortman (Ben Gurion University of the Negev).
Funded by the Israel Ministry of Science and Technology (MOST).